In the era of targeted therapy in oncology very expensive, it is important to look for cheap labor that could be active in preventing cancer and then have a huge impact on public health, Decensi said in a statement.A small study suggests that taking allopurinol, a drug that has been used to treat gout for over 20 years, could reduce the growth of colon cancer and reduce the risk of colon cancer.
Decensi conducted a clinical study of 73 patients with colorectal polyps, which were treated with allopurinol between 2006 and 2010. The researchers collected samples of tissue samples from patients to compare normal and abnormal levels of Ki67. The research team reported that allopurinol is a very safe medication, and if we consider only a few side effects have been reported ? three mild gastrointestinal events.
Allopurinol, sold under the brand names and Lopurin Zyloprim reduces the activity of reactive oxygen metabolites. Previous research has also shown that patients treated with allopurinol gout had a reduced risk of colorectal cancer, one of the most frequently diagnosed cancer in men and women in the U. S. According to 2010 statistics from the American Cancer Society, there was about 102 900 new cases of colon cancer and 39,670 new cases of rectal cancer.
Even before the study was completed, an initial analysis of samples of normal tissue showed no difference between patients treated with placebo and those taking allopurinol. Among the first 13 patients enrolled in the study, the results showed that levels of Ki67 in normal tissues was doubled in patients taking placebo, compared with an increase of only 5 percent in patients treated with either dose of allopurinol.
The researcher Andrea Decensi, MD, director of the department of medical oncology at the Galliera Hospital in Genoa, Italy, presented the results of the study of the American Association ninth annual Frontiers cancer research at the Conference on the Prevention of Cancer Research held in Philadelphia.
According to the authors, the study found that children stating a dislike of school were 2.5 times more likely to have sexual intercourse.
Dislike of school also strongly predicted alcohol use.
Posted in health
Source: http://www.chircovskiidanceproject.com/drop-the-medicine-can-reduce-colorectal-cancer/
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